Phenotypes associated with this allele

• Allele Symbol: Satb1^{tm1a(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:4436287
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Satb1^tm1a(EUCOMM)Hmgu/Satb1^tm1a(EUCOMM)Hmgu	involves: C57BL/6N	MGI:5491492

Genotype
MGI:5491492

hm1

• Allelic Composition: Satb1^{tm1a(EUCOMM)Hmgu}/Satb1^{tm1a(EUCOMM)Hmgu}
• Genetic Background: involves: C57BL/6N
• Cell Lines: HEPD0534_5_E11

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:196342 )

• mice die within three weeks of birth

nervous system

nervous system phenotype ( J:196342 )

N • mice exhibit normal cortical lamination

abnormal brain interneuron morphology ( J:196342 )

• reduced numbers of somatostatin+ cortical interneurons at P15

• however, the number of tangential migrating interneurons during embryogenesis is normal

growth/size/body

postnatal growth retardation ( J:196342 )

• mice fail to thrive