Phenotypes associated with this allele

• Allele Symbol: Ino80^{tm1a(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:4436542
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ino80^tm1a(EUCOMM)Hmgu/Ino80^tm1a(EUCOMM)Hmgu	C57BL/6N-Ino80^tm1a(EUCOMM)Hmgu/Ics	MGI:5757253
ht2	Ino80^tm1a(EUCOMM)Hmgu/Ino80^+	C57BL/6N-Ino80^tm1a(EUCOMM)Hmgu/Ics	MGI:5757252

Genotype
MGI:5757253

hm1

• Allelic Composition: Ino80^{tm1a(EUCOMM)Hmgu}/Ino80^{tm1a(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Ino80^{tm1a(EUCOMM)Hmgu}/Ics
• Cell Lines: HEPD0509_6_D10

Data Sources

IMPC Data for Ino80

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - ICS

Genotype
MGI:5757252

ht2

• Allelic Composition: Ino80^{tm1a(EUCOMM)Hmgu}/Ino80⁺
• Genetic Background: C57BL/6N-Ino80^{tm1a(EUCOMM)Hmgu}/Ics
• Cell Lines: HEPD0509_6_D10

Data Sources

IMPC Data for Ino80

behavior/neurological

decreased exploration in new environment ( J:211773 )

IMPC - ICS

increased aggression ( J:211773 )

IMPC - ICS

decreased locomotor activity ( J:211773 )

♂

IMPC - ICS

abnormal vocalization ( J:211773 )

♀

IMPC - ICS

cardiovascular system

prolonged QRS complex duration ( J:211773 )

♀

IMPC - ICS

endocrine/exocrine glands

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - ICS

reproductive system

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - ICS