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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ush1ctm1.1Mull
targeted mutation 1.1, Ulrich Mueller
MGI:4436726
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ush1ctm1.1Mull/Ush1ctm1.1Mull involves: 129S/SvEv * C57BL/6 * SJL MGI:4436727


Genotype
MGI:4436727
hm1
Allelic
Composition		 Ush1ctm1.1Mull/Ush1ctm1.1Mull
Genetic
Background		 involves: 129S/SvEv * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ush1ctm1.1Mull mutation (0 available); any Ush1c mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
abnormal cochlear hair cell stereociliary bundle morphology ( J:157359 )
• hair bundle morphology is disrupted at P5
increased or absent threshold for auditory brainstem response ( J:157359 )
• at 4 weeks of age thresholds are greater than 90 dB
deafness ( J:157359 )
• at 4 weeks of age

nervous system
abnormal cochlear hair cell stereociliary bundle morphology ( J:157359 )
• hair bundle morphology is disrupted at P5

behavior/neurological
head tossing ( J:157359 )
• from P10 onward
circling ( J:157359 )
• from P10 onward




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory