All Phenotypes H2-Ab1<b-tm1.1Sish> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

H2-Ab1^b-tm1.1Sish
targeted mutation 1.1, Satoshi Ishido
MGI:4436864

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	H2-Ab1^b-tm1.1Sish/H2-Ab1^b-tm1.1Sish	involves: 129S1/Sv * 129X1/SvJ	MGI:4436874

Allelic Composition	H2-Ab1^b-tm1.1Sish/H2-Ab1^b-tm1.1Sish
Genetic Background	involves: 129S1/Sv * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2-Ab1^b-tm1.1Sish mutation (1 available); any H2-Ab1 mutation (83 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal dendritic cell physiology ( J:157516 )

• CD11c+ dendritic cells induce less proliferation of CD4+ T cell expressing Tg(TcraTcrb)425Cbn compared with wild-type cells

decreased interleukin-12 secretion ( J:157516 )

• in CD8+ and CD8- dendritic cells following LPS stimulation

decreased tumor necrosis factor secretion ( J:157516 )

• in CD8+ and CD8- dendritic cells following LPS stimulation

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24