All Phenotypes Adam24<tm1Pmkf> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Adam24^tm1Pmkf
targeted mutation 1, Paul Primakoff
MGI:4437125

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Adam24^tm1Pmkf/Adam24^tm1Pmkf	involves: C57BL/6J	MGI:4437127

Allelic Composition	Adam24^tm1Pmkf/Adam24^tm1Pmkf
Genetic Background	involves: C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adam24^tm1Pmkf mutation (0 available); any Adam24 mutation (31 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

In vivo polyspermy with Adam24^tm1Pmkf/Adam24^tm1Pmkf male mice

reproductive system

reduced male fertility ( J:157046 )

• male mice are subfertile with wild-type males producing more than twice as many fetuses

polyspermy ( J:157046 )

• the mean number of fused sperm per oocyte is increased in vitro using zona free oocytes

• increased levels of polyspermic oocytes in vivo

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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