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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(APOE-ABCG1)1Ssf
transgene insertion 1, Silvia Santamarina-Fojo
MGI:4438467
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(APOE-ABCG1)1Ssf/? C57BL/6-Tg(APOE-ABCG1)1Ssf MGI:5140082


Genotype
MGI:5140082
tg1
Allelic
Composition		 Tg(APOE-ABCG1)1Ssf/?
Genetic
Background		 C57BL/6-Tg(APOE-ABCG1)1Ssf
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(APOE-ABCG1)1Ssf mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating HDL cholesterol level ( J:94077 )
• small, but significant reduction in plasma HDL-C
increased liver cholesterol level ( J:94077 )
• increase in biliary cholesterol from common bile duct
abnormal phospholipid level ( J:94077 )
• increase in phospholipid secretion rates from common bile duct

liver/biliary system
increased liver cholesterol level ( J:94077 )
• increase in biliary cholesterol from common bile duct




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory