About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(APOE-ABCG1)1Ssf
transgene insertion 1, Silvia Santamarina-Fojo
MGI:4438467
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(APOE-ABCG1)1Ssf/? C57BL/6-Tg(APOE-ABCG1)1Ssf MGI:5140082


Genotype
MGI:5140082
tg1
Allelic
Composition
Tg(APOE-ABCG1)1Ssf/?
Genetic
Background
C57BL/6-Tg(APOE-ABCG1)1Ssf
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(APOE-ABCG1)1Ssf mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• small, but significant reduction in plasma HDL-C
• increase in biliary cholesterol from common bile duct
• increase in phospholipid secretion rates from common bile duct

liver/biliary system
• increase in biliary cholesterol from common bile duct





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory