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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Slc20a1tm1.1Lbek
targeted mutation 1.1, Laurent Beck
MGI:4438613
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Slc20a1tm1.1Lbek/Slc20a1tm1.1Lbek involves: 129S2/SvPas * C57BL/6 * C57BL/6J * SJL MGI:4438615
cn2
 		Slc20a1tm1.1Lbek/Slc20a1tm1.1Lbek
Tg(Mx1-cre)1Cgn/0 		involves: 129S2/SvPas * C57BL/6 * C57BL/6J * CBA MGI:5474455


Genotype
MGI:4438615
hm1
Allelic
Composition		 Slc20a1tm1.1Lbek/Slc20a1tm1.1Lbek
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc20a1tm1.1Lbek mutation (0 available); any Slc20a1 mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:157997 )
• viable with no gross abnormalities




Genotype
MGI:5474455
cn2
Allelic
Composition		 Slc20a1tm1.1Lbek/Slc20a1tm1.1Lbek
Tg(Mx1-cre)1Cgn/0
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * C57BL/6J * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc20a1tm1.1Lbek mutation (0 available); any Slc20a1 mutation (36 available)
Tg(Mx1-cre)1Cgn mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
enlarged spleen ( J:194198 )
• in pIpC-treated mice
spleen hyperplasia ( J:194198 )
• in pIpC-treated mice
abnormal definitive hematopoiesis ( J:194198 )
• in an in vitro hematopoietic progenitor assay, spleen samples from pIpC-treated mice produce more granulocyte/macrophages, erythroid cells and immature red blood cells compared with wild-type spleen samples
decreased erythrocyte cell number ( J:194198 )
• in pIpC-treated mice
increased leukocyte cell number ( J:194198 )
• in pIpC-treated mice

immune system
enlarged spleen ( J:194198 )
• in pIpC-treated mice
spleen hyperplasia ( J:194198 )
• in pIpC-treated mice
increased leukocyte cell number ( J:194198 )
• in pIpC-treated mice

growth/size/body
enlarged spleen ( J:194198 )
• in pIpC-treated mice
spleen hyperplasia ( J:194198 )
• in pIpC-treated mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory