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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Snap23tm1.1Paro
targeted mutation 1.1, Paul A Roche
MGI:4439388
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Snap23tm1.1Paro/Snap23tm1.1Paro involves: 129S1/Sv MGI:4439391
hm2
 		Snap23tm1.1Paro/Snap23tm1.1Paro involves: 129S1/Sv * C57BL/6 MGI:5006858


Genotype
MGI:4439391
hm1
Allelic
Composition		 Snap23tm1.1Paro/Snap23tm1.1Paro
Genetic
Background		 involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Snap23tm1.1Paro mutation (0 available); any Snap23 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:5006858
hm2
Allelic
Composition		 Snap23tm1.1Paro/Snap23tm1.1Paro
Genetic
Background		 involves: 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Snap23tm1.1Paro mutation (0 available); any Snap23 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality before implantation, complete penetrance ( J:171444 )
• blastocysts recovered at E3.5 are grossly abnormal and appear to be dying

embryo
abnormal blastocyst morphology ( J:171444 )
• at E3.5 are grossly abnormal and have not expanded properly




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory