Phenotypes associated with this allele

• Allele Symbol: Tbc1d32^bromi
• Allele Name: bromi
• Allele ID: MGI:4440463
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tbc1d32^bromi/Tbc1d32^bromi	involves: C57BL/6J	MGI:4440465
ht2	Tbc1d32^bromi/Tbc1d32^Gt(RRF165)Byg	involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J	MGI:4440467

Genotype
MGI:4440465

hm1

• Allelic Composition: Tbc1d32^bromi/Tbc1d32^bromi
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal retina pigment epithelium morphology ( J:158583 )

• reduced

small lens ( J:158583 )

abnormal eye development ( J:158583 )

• mice have poorly developed eyes compared with wild-type mice

retina hypoplasia ( J:158583 )

nervous system

abnormal neural tube morphology ( J:158583 )

• mice lack cephalic ventral midline furrows unlike wild-type mice

abnormal embryonic neuroepithelium morphology ( J:158583 )

• neuroepithelial cilia are bulbous or spherical unlike in wild-type mice

exencephaly ( J:158583 )

limbs/digits/tail

preaxial polydactyly ( J:158583 )

embryo

abnormal neural tube morphology ( J:158583 )

• mice lack cephalic ventral midline furrows unlike wild-type mice

abnormal embryonic neuroepithelium morphology ( J:158583 )

• neuroepithelial cilia are bulbous or spherical unlike in wild-type mice

pigmentation

abnormal retina pigment epithelium morphology ( J:158583 )

• reduced

Genotype
MGI:4440467

ht2

• Allelic Composition: Tbc1d32^bromi/Tbc1d32^{Gt(RRF165)Byg}
• Genetic Background: involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J

nervous system

exencephaly ( J:158583 )

vision/eye

abnormal eye development ( J:158583 )

• mice have poorly developed eyes compared with wild-type mice