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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Uhrf1tm1Hko
targeted mutation 1, Haruhiko Koseki
MGI:4440836
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Uhrf1tm1Hko/Uhrf1tm1Hko Not Specified MGI:4440837


Genotype
MGI:4440837
hm1
Allelic
Composition
Uhrf1tm1Hko/Uhrf1tm1Hko
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Uhrf1tm1Hko mutation (0 available); any Uhrf1 mutation (52 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

embryo
• increased apoptosis in cephalic mesoderm at E9.5
• developmental arrest after gastrulation
• failure of outgrowth of allantois

cellular
• global CpG methylation is substantially reduced

nervous system
• increased apoptosis in the ventral region of the neurtaql tubre at E9.5

craniofacial

skeleton
• increased apoptosis at E9.5

growth/size/body





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory