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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Prox1tm5(GFP/cre)Gco
targeted mutation 5, Guillermo Oliver
MGI:4441289
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Prox1tm5(GFP/cre)Gco/Prox1+ involves: 129S1/Sv * NMRI MGI:4441389
ht2
Prox1tm1Gco/Prox1tm5(GFP/cre)Gco involves: 129S1/Sv * 129X1/SvJ * NMRI MGI:4441390


Genotype
MGI:4441389
ht1
Allelic
Composition
Prox1tm5(GFP/cre)Gco/Prox1+
Genetic
Background
involves: 129S1/Sv * NMRI
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prox1tm5(GFP/cre)Gco mutation (0 available); any Prox1 mutation (43 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• exhibited on this background
• Background Sensitivity: on all other backgrounds tested (no data provided), lethality is nearly 100%




Genotype
MGI:4441390
ht2
Allelic
Composition
Prox1tm1Gco/Prox1tm5(GFP/cre)Gco
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * NMRI
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prox1tm1Gco mutation (0 available); any Prox1 mutation (43 available)
Prox1tm5(GFP/cre)Gco mutation (0 available); any Prox1 mutation (43 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• only a few scattered lymphatic endothelial cells (LECs) are found at E11.5





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory