Phenotypes associated with this allele

• Allele Symbol: Tcf7^{tm1a(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4441645
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tcf7^tm1a(EUCOMM)Wtsi/Tcf7^tm1a(EUCOMM)Wtsi	C57BL/6N-Tcf7^tm1a(EUCOMM)Wtsi/Ics	MGI:5782205

Genotype
MGI:5782205

hm1

• Allelic Composition: Tcf7^{tm1a(EUCOMM)Wtsi}/Tcf7^{tm1a(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Tcf7^{tm1a(EUCOMM)Wtsi}/Ics
• Cell Lines: EPD0023_2_A12

Data Sources

IMPC Data for Tcf7

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal response to tactile stimuli ( J:165965 )

♀

IMPC - ICS

hematopoietic system

increased B cell number ( J:165965 )

♂

IMPC - ICS

decreased T cell number ( J:165965 )

♂

IMPC - ICS

decreased CD4-positive, alpha-beta T cell number ( J:165965 )

♂

IMPC - ICS

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:165965 )

♂

IMPC - ICS

immune system

increased B cell number ( J:165965 )

♂

IMPC - ICS

decreased T cell number ( J:165965 )

♂

IMPC - ICS

decreased CD4-positive, alpha-beta T cell number ( J:165965 )

♂

IMPC - ICS

limbs/digits/tail

syndactyly ( J:165965 )

♀

IMPC - ICS

abnormal forelimb morphology ( J:165965 )

♀

IMPC - ICS

vision/eye

cataract ( J:165965 )

♂

IMPC - ICS