About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Nckipsdtm1.2Toft
targeted mutation 1.2, Tomoko Fukumi-Tominaga
MGI:4442818
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Nckipsdtm1.2Toft/Nckipsdtm1.2Toft involves: 129S2/SvPas * C57BL/6 * FVB/N MGI:4442826


Genotype
MGI:4442826
hm1
Allelic
Composition
Nckipsdtm1.2Toft/Nckipsdtm1.2Toft
Genetic
Background
involves: 129S2/SvPas * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nckipsdtm1.2Toft mutation (0 available); any Nckipsd mutation (27 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• mouse embryonic fibroblasts are longer and thinner with more stress fibers than wild-type cells
• mouse embryonic fibroblasts exhibit impaired cell adhesion compared with wild-type cells
• serum-starved mouse embryonic stem cells exhibit reduced motility compared with wild-type cells

growth/size/body
N
• mice exhibit normal growth

reproductive system
N
• mice exhibit normal fertilization





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory