cellular
• mouse embryonic fibroblasts are longer and thinner with more stress fibers than wild-type cells
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• mouse embryonic fibroblasts exhibit impaired cell adhesion compared with wild-type cells
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• serum-starved mouse embryonic stem cells exhibit reduced motility compared with wild-type cells
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growth/size/body
N |
• mice exhibit normal growth
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reproductive system
N |
• mice exhibit normal fertilization
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