About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Muc2m2Btlr
mutation 2, Bruce Beutler
MGI:4442897
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ot1
 		Muc2m2Btlr/? C57BL/6J-Muc2m2Btlr MGI:4442898


Genotype
MGI:4442898
ot1
Allelic
Composition		 Muc2m2Btlr/?
Genetic
Background		 C57BL/6J-Muc2m2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Muc2m2Btlr mutation (1 available); any Muc2 mutation (84 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
increased susceptibility to induced colitis ( J:159359 )
• on days 6 and 7 of exposure to 1% dextran sulfate sodium (DSS) in their drinking water, mice with this mutation exhibit more severe bleeding and weight loss than wild-type C57BL/6J mice

immune system
increased susceptibility to induced colitis ( J:159359 )
• on days 6 and 7 of exposure to 1% dextran sulfate sodium (DSS) in their drinking water, mice with this mutation exhibit more severe bleeding and weight loss than wild-type C57BL/6J mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory