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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Agtpbp1m2Btlr
mutation 2, Bruce Beutler
MGI:4442903
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Agtpbp1m2Btlr/Agtpbp1m2Btlr C57BL/6J-Agtpbp1m2Btlr MGI:4442904


Genotype
MGI:4442904
hm1
Allelic
Composition		 Agtpbp1m2Btlr/Agtpbp1m2Btlr
Genetic
Background		 C57BL/6J-Agtpbp1m2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agtpbp1m2Btlr mutation (0 available); any Agtpbp1 mutation (66 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological

growth/size/body
decreased body size ( J:159361 )
• mutant mice are slightly smaller than wild-type littermates

reproductive system
decreased activated sperm motility ( J:159361 )
• sperm from homozygous mutant male mice exhibit only 50% normal motility
• intracytoplasmic sperm injection (ICSI) of homozygous mutant sperm into C57BL/6J wild-type oocytes yields progeny

cellular
decreased activated sperm motility ( J:159361 )
• sperm from homozygous mutant male mice exhibit only 50% normal motility
• intracytoplasmic sperm injection (ICSI) of homozygous mutant sperm into C57BL/6J wild-type oocytes yields progeny




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory