All Phenotypes Mfn2<tm1.1Balo> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mfn2^tm1.1Balo
targeted mutation 1.1, Robert Balo
MGI:4442975

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mfn2^tm1.1Balo/Mfn2^tm1.1Balo	Not Specified	MGI:4442985

Allelic Composition	Mfn2^tm1.1Balo/Mfn2^tm1.1Balo
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mfn2^tm1.1Balo mutation (0 available); any Mfn2 mutation (27 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• mice die between E12.5 and birth

nervous system

abnormal axonal transport ( J:159219 )

• neurons exhibit abnormal mitochondria transport and delayed migration of mitochondria into the axons compared with wild-type cells

• however, transport of other organelles is normal

cellular

abnormal mitochondrial physiology ( J:159219 )

• neurons exhibit abnormal mitochondria transport and delayed migration of mitochondria into the axons compared with wild-type cells

• however, transport of other organelles is normal

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24