All Phenotypes Dact1<tm1.2Bnrc> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Dact1^tm1.2Bnrc
targeted mutation 1.2, Benjamin N R Cheyette
MGI:4442991

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Dact1^tm1.1Bnrc/Dact1^tm1.2Bnrc Emx1^tm1(cre)Krj/Emx1⁺	involves: 129S2/SvPas	MGI:4442996

Allelic Composition	Dact1^tm1.1Bnrc/Dact1^tm1.2Bnrc Emx1^tm1(cre)Krj/Emx1⁺
Genetic Background	involves: 129S2/SvPas

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dact1^tm1.1Bnrc mutation (0 available); any Dact1 mutation (21 available)
Dact1^tm1.2Bnrc mutation (1 available); any Dact1 mutation (21 available)
Emx1^tm1(cre)Krj mutation (2 available); any Emx1 mutation (34 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:159217 )

N	• mice exhibit normal cellular organization and regional anatomy of the brain

abnormal dendritic spine morphology ( J:159217 )

• cultured hippocampal neurons exhibit reduced dendritic spine density, spine length, and spine head width compared with wild-type neurons

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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