About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm1.1(CAG-Trp53*,-EGFP)Medz
targeted mutation 1.1, Ruslan Medzhltov
MGI:4443071
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gt(ROSA)26Sortm1.1(CAG-Trp53*,-EGFP)Medz/Gt(ROSA)26Sortm1.1(CAG-Trp53*,-EGFP)Medz involves: C57BL/6 MGI:4443112


Genotype
MGI:4443112
hm1
Allelic
Composition		 Gt(ROSA)26Sortm1.1(CAG-Trp53*,-EGFP)Medz/Gt(ROSA)26Sortm1.1(CAG-Trp53*,-EGFP)Medz
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1.1(CAG-Trp53*,-EGFP)Medz mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased thymocyte apoptosis ( J:158953 )
• in response to irradiation

immune system
decreased thymocyte apoptosis ( J:158953 )
• in response to irradiation

cellular
decreased thymocyte apoptosis ( J:158953 )
• in response to irradiation

endocrine/exocrine glands
decreased thymocyte apoptosis ( J:158953 )
• in response to irradiation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory