Allele Symbol Allele Name Allele ID |
Sall1tm4.1Ryn targeted mutation 4.1, Ryuichi Nishinakamura MGI:4443121 |
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Summary |
3 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• mutants do not survive after birth with tamoxifen treatment on E12.5
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• tubular structures are reduced at E14.5
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• with i.p. tamoxifen delivery to pregnant dams on E12.5, kidney size is significantly reduced at E18.5
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• numbers of proximal and distale tubules are significantly reduced compared to controls, but glomerular development is not significantly affected
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• embryonic stem cells treated with cre-expressing adenovirus exhibit impaired proliferation compared with wild-type cells
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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