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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Esrp1m1Btlr
mutation 1, Bruce Beutler
MGI:4450974
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Esrp1m1Btlr/Esrp1m1Btlr involves: C57BL/6J MGI:5515349
ht2
 		Esrp1m1Btlr/Esrp1tm1.2Rpc involves: 129S4/SvJae * C57BL/6 * C57BL/6J MGI:7437694


Genotype
MGI:5515349
hm1
Allelic
Composition		 Esrp1m1Btlr/Esrp1m1Btlr
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Esrp1m1Btlr mutation (1 available); any Esrp1 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
hyperactivity ( J:201716 )
• may be more penetrant on a mixed C3H x C57BL/6J background
circling ( J:201716 )
• may be more penetrant on a mixed C3H x C57BL/6J background

hearing/vestibular/ear




Genotype
MGI:7437694
ht2
Allelic
Composition		 Esrp1m1Btlr/Esrp1tm1.2Rpc
Genetic
Background		 involves: 129S4/SvJae * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Esrp1m1Btlr mutation (1 available); any Esrp1 mutation (19 available)
Esrp1tm1.2Rpc mutation (1 available); any Esrp1 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
cleft secondary palate ( J:293624 )
• cleft of secondary hard and soft palate
• no cleft lip or cleft of the primary palate

digestive/alimentary system
cleft secondary palate ( J:293624 )
• cleft of secondary hard and soft palate
• no cleft lip or cleft of the primary palate

growth/size/body
cleft secondary palate ( J:293624 )
• cleft of secondary hard and soft palate
• no cleft lip or cleft of the primary palate




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory