Analysis Tools|
Allele Symbol Allele Name Allele ID |
Tg(CD19-Tnfsf7)#Rvl transgene insertion, Rene A W van Lier MGI:4452498 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• spleens lack T cells
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• spleens lack T cells
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• transitional-1 B cells are reduced at 4 weeks of age and declining over time
• transitional-2 B cells decline after 6 to 8 weeks
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• mature B cells are reduced at 4 weeks of age and declining over time
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• marginal metallophilic macrophages decline more gradually than marginal zone macrophages
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• B cell follicles are reduced in size
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• marginal zone macrophages decline in number at 5 weeks
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• transitional-1 B cells are reduced at 4 weeks of age and declining over time
• transitional-2 B cells decline after 6 to 8 weeks
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• mature B cells are reduced at 4 weeks of age and declining over time
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• marginal metallophilic macrophages decline more gradually than marginal zone macrophages
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• B cell follicles are reduced in size
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• marginal zone macrophages decline in number at 5 weeks
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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