Analysis Tools
homeostasis/metabolism
| N |
• mice exhibit normal metabolic parameters whether fed standard chow or a high-fat diet
• mice exhibit normal lipid handling whether fed standard chow or a high-fat diet
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• in male, but not female, mice fed a high-fat diet
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• in male, but not female, mice fed a high-fat diet
• however, mice fed a low fat diet exhibit normal fasting blood glucose and insulin levels, glucose, and insulin tolerance, and glucose-stimulated insulin secretion
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• mice fed a high-fat diet exhibit reduced liver fibrosis, oxidative and endoplasmic stress and reduced adipose tissue inflammation with increased macrophage compared with wild-type mice
• however, mice exhibit normal liver histology, hepatic triglyceride and cholesterol content
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growth/size/body
| N |
• mice exhibit normal weight, fat mass and lean mass whether fed standard chow or a high-fat diet
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liver/biliary system
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• in mice fed a high-fat diet
• however, mice exhibit normal liver histology, hepatic triglyceride and cholesterol content
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immune system
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• 4.5-fold in the adipose tissue of mice fed a high-fat diet
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hematopoietic system
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• 4.5-fold in the adipose tissue of mice fed a high-fat diet
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