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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Saa3tm1(KOMP)Vlcg
targeted mutation 1, Velocigene
MGI:4452947
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Saa3tm1(KOMP)Vlcg/Saa3tm1(KOMP)Vlcg involves: C57BL/6NTac MGI:6147628
ht2
Saa3tm1(KOMP)Vlcg/Saa3+ involves: C57BL/6NTac MGI:6147629


Genotype
MGI:6147628
hm1
Allelic
Composition
Saa3tm1(KOMP)Vlcg/Saa3tm1(KOMP)Vlcg
Genetic
Background
involves: C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Saa3tm1(KOMP)Vlcg mutation (1 available); any Saa3 mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
N
• mice fed standard chow or a high-fat diet and high-sugar diet exhibit normal oxygen consumption, carbon dioxide production, heat production, respiratory quotient, food intake and glucose metabolism
• on a high-fat diet and high-sugar diet
• however, body composition is normal
• in fasting female mice fed a high-fat diet and high-sugar diet
• in fasting female mice fed a high-fat diet and high-sugar diet
• in fasting female mice fed a high-fat diet and high-sugar diet

growth/size/body
• on a high-fat diet and high-sugar diet
• however, body composition is normal

adipose tissue
• in male, but not female, mice fed a high-fat diet and high-sugar diet

liver/biliary system
• in male, but not female, mice fed a high-fat diet and high-sugar diet

immune system




Genotype
MGI:6147629
ht2
Allelic
Composition
Saa3tm1(KOMP)Vlcg/Saa3+
Genetic
Background
involves: C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Saa3tm1(KOMP)Vlcg mutation (1 available); any Saa3 mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• in fasting female mice fed a high-fat diet and high-sugar diet





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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory