All Phenotypes Lrp5<tm2Mawa> MGI Mouse

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Lrp5^tm2Mawa
targeted mutation 2, Matthew Warman
MGI:4453225

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Lrp5^tm2Mawa/Lrp5⁺	involves: 129S1/Sv * 129X1/SvJ	MGI:5014221
cn2	Lrp5^tm2Mawa/Lrp5⁺ Tg(Dmp1-cre)1Jqfe/0	involves: 129S1/Sv * 129S1/SvImj * 129X1/SvJ * FVB/N	MGI:5014223
cn3	Lrp5^tm2Mawa/Lrp5⁺ Tg(Vil1-cre)997Gum/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL	MGI:5014228
cn4	Lrp5^tm2Mawa/Lrp5⁺ Tg(Prrx1-cre)1Cjt/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL	MGI:5014231

Allelic Composition	Lrp5^tm2Mawa/Lrp5⁺
Genetic Background	involves: 129S1/Sv * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp5^tm2Mawa mutation (2 available); any Lrp5 mutation (82 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

skeleton phenotype ( J:172746 )

N	• normal bone mass

Allelic Composition	Lrp5^tm2Mawa/Lrp5⁺ Tg(Dmp1-cre)1Jqfe/0
Genetic Background	involves: 129S1/Sv * 129S1/SvImj * 129X1/SvJ * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp5^tm2Mawa mutation (2 available); any Lrp5 mutation (82 available)
Tg(Dmp1-cre)1Jqfe mutation (4 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

increased bone mass ( J:172746 )

Allelic Composition	Lrp5^tm2Mawa/Lrp5⁺ Tg(Vil1-cre)997Gum/0
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp5^tm2Mawa mutation (2 available); any Lrp5 mutation (82 available)
Tg(Vil1-cre)997Gum mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

skeleton phenotype ( J:172746 )

N	• normal bone mass

Allelic Composition	Lrp5^tm2Mawa/Lrp5⁺ Tg(Prrx1-cre)1Cjt/0
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp5^tm2Mawa mutation (2 available); any Lrp5 mutation (82 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

increased bone mass ( J:172746 )

• in the limbs but not in the spine

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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