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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tbx1tm3.1Bld
targeted mutation 3.1, Antonio Baldini
MGI:4453450
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Tbx1tm3.1Bld/Tbx1tm6(cre)Bld 		involves: 129S4/SvJaeSor * 129S7/SvEvBrd MGI:4453458


Genotype
MGI:4453458
cn1
Allelic
Composition		 Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Tbx1tm3.1Bld/Tbx1tm6(cre)Bld
Genetic
Background		 involves: 129S4/SvJaeSor * 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1Sor mutation (7 available); any Gt(ROSA)26Sor mutation (993 available)
Tbx1tm3.1Bld mutation (1 available); any Tbx1 mutation (36 available)
Tbx1tm6(cre)Bld mutation (1 available); any Tbx1 mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal lymphatic vessel morphology ( J:159824 )
• abnormal lymphatic vessels fail to extend into distal mesentery unlike in wild-type mice
• between E15.5 and E16.5, lymphatic vessels are almost completely lost unlike in wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory