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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Plpp5tm1(KOMP)Mbp
targeted mutation 1, Mouse Biology Program, UC Davis
MGI:4453994
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Plpp5tm1(KOMP)Mbp/Plpp5tm1(KOMP)Mbp involves: C57BL/6N MGI:6281120
cx2
Plpp5tm1(KOMP)Mbp/Plpp5tm1(KOMP)Mbp
Prdm1tm1Nutt/Prdm1+
involves: C57BL/6 * C57BL/6N MGI:6281123


Genotype
MGI:6281120
hm1
Allelic
Composition
Plpp5tm1(KOMP)Mbp/Plpp5tm1(KOMP)Mbp
Genetic
Background
involves: C57BL/6N
Cell Lines DEPD00512_4_E01
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plpp5tm1(KOMP)Mbp mutation (0 available); any Plpp5 mutation (12 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• mice are viable and fertile, show no overt physical defects or disease phenotype, and exhibit no differences in the development, maturation and differentiation of B-lymphocytes into antibody secreting cells or in immunoglobulin class-switch recombination relative to wild-type controls




Genotype
MGI:6281123
cx2
Allelic
Composition
Plpp5tm1(KOMP)Mbp/Plpp5tm1(KOMP)Mbp
Prdm1tm1Nutt/Prdm1+
Genetic
Background
involves: C57BL/6 * C57BL/6N
Cell Lines DEPD00512_4_E01
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plpp5tm1(KOMP)Mbp mutation (0 available); any Plpp5 mutation (12 available)
Prdm1tm1Nutt mutation (1 available); any Prdm1 mutation (66 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• mice show no significant differences in the frequency of bone marrow plasma cells, splenic plasma cells and splenic plasmablasts, or in the serum concentrations of IgM, IgG1, IgG2b, IgG2c, IgG3 or IgA relative to wild-type controls





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory