Phenotypes associated with this allele

• Allele Symbol: Mesp2^{tm15.1(Lfng)Ysa}
• Allele Name: targeted mutation 15.1, Yumiko Saga
• Allele ID: MGI:4454334
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mesp2^tm15.1(Lfng)Ysa/Mesp2^tm15.1(Lfng)Ysa	Not Specified	MGI:4454335
cx2	Lfng^tm1Rjo/Lfng^tm1Rjo Mesp2^tm15.1(Lfng)Ysa/Mesp2^+	involves: 129S7/SvEvBrd	MGI:4454336

Genotype
MGI:4454335

hm1

• Allelic Composition: Mesp2^{tm15.1(Lfng)Ysa}/Mesp2^{tm15.1(Lfng)Ysa}
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal somite development ( J:159983 )

• expression of Lfng does not rescue the Mesp2 null phenotype

Genotype
MGI:4454336

cx2

• Allelic Composition: Lfng^tm1Rjo/Lfng^tm1Rjo; Mesp2^{tm15.1(Lfng)Ysa}/Mesp2⁺
• Genetic Background: involves: 129S7/SvEvBrd

embryo

abnormal somite development ( J:159983 )

• the segmental morphology in the developing embryos is similar to that in Lfng^tm1Rjo single homozygotes

abnormal dorsal-ventral polarity of the somites ( J:159983 )

• abnormal vertebral morphology along the anteroposterior axis as is seen in Lfng^tm1Rjo single homozygotes