homeostasis/metabolism
• at E15.5, mice exhibit edema unlike wild-type mice
• however, flp mediated recombination to remove the neo cassette restores wild-type phenotype
|
immune system
• at E15.5, mice exhibit abnormally patterned lymph sacs compared with wild-type mice as determined by marker expression
• however, flp mediated recombination to remove the neo cassette restores lymphangiogenesis
|