All Phenotypes Adamts4<tm1Dqp> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Adamts4^tm1Dqp
targeted mutation 1, Duanqing Pei
MGI:4454664

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Adamts4^tm1Dqp/Adamts4^tm1Dqp	involves: 129X1/SvJ * C57BL/6J	MGI:5007491

Allelic Composition	Adamts4^tm1Dqp/Adamts4^tm1Dqp
Genetic Background	involves: 129X1/SvJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adamts4^tm1Dqp mutation (0 available); any Adamts4 mutation (49 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Abnormal Purkinje cell morphology in the Sparcl1^tm1Pmc/Sparcl1^tm1Pmc and Adamts4^tm1Dqp/Adamts4^tm1Dqp cerebellum

nervous system

abnormal Purkinje cell morphology ( J:159752 )

• mice exhibit stunted and less branched processes extending from extending from Purkinje cell bodies compared to in wild-type mice

gliosis ( J:159752 )

• mice exhibit an increase in glial cells compared to in wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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