Phenotypes associated with this allele

• Allele Symbol: Stard4^tm1.2Bres
• Allele Name: targeted mutation 1.2, Jan L Breslow
• Allele ID: MGI:4456146
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Stard4^tm1.2Bres/Stard4^tm1.2Bres	involves: BALB/cJ * C57BL/6 * C57BL/6J * SJL	MGI:4456148

Genotype
MGI:4456148

hm1

• Allelic Composition: Stard4^tm1.2Bres/Stard4^tm1.2Bres
• Genetic Background: involves: BALB/cJ * C57BL/6 * C57BL/6J * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:160807 )

N • mice exhibit normal glucose homeostasis

decreased circulating cholesterol level ( J:160807 )

• female mice fed a 0.5% cholesterol diet exhibit decreased circulating total cholesterol, LDL, and cholesterol esters compared with similarly treated wild-type mice

• however, male mice fed a 0.5% cholesterol diet exhibit normal circulating cholesterol levels

decreased circulating LDL cholesterol level ( J:160807 )

• in female mice fed a 0.5% cholesterol diet

growth/size/body

growth/size/body region phenotype ( J:160807 )

N • mice exhibit normal body composition

decreased body weight ( J:160807 )

• in male mice beginning at 5 weeks of age and in female mice at 12 weeks

decreased body length ( J:160807 )

• at 12 weeks in male mice

liver/biliary system

decreased liver weight ( J:160807 )

• at 12 weeks in male mice and later in female mice

abnormal bile composition ( J:160807 )

• when fed standard chow, female mice exhibit a decrease in total bile cholesterol and phospholipids compared to in wild-type mice

• however, male mice exhibit normal bile composition

behavior/neurological

behavior/neurological phenotype ( J:160807 )

N • mice exhibit normal food intake