mortality/aging
• mice exhibit embryonic lethality at E7.5
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Allele Symbol Allele Name Allele ID |
Pknox1tm1Ngc targeted mutation 1, Neal G Copeland MGI:4459452 |
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Summary |
2 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• mice exhibit embryonic lethality at E7.5
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• median survival time is 23 weeks compared with 58 weeks for Tg(IghMyc)22Bri mice
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• in the spleen
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• in the spleen
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• accelerated and enhanced immature B cell lymphomas compared with Tg(IghMyc)22Bri mice
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• in the spleen
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• in the spleen
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• in the spleen
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• in the spleen
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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