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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fpr2tm1.1Jimw
targeted mutation 1.1, Ji Ming Wang
MGI:4459724
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Fpr2tm1.1Jimw/Fpr2tm1.1Jimw
Lyz2tm1(cre)Ifo/Lyz2+ 		involves: 129P2/OlaHsd * 129X1/SvJ MGI:5503981
cn2
 		Fpr2tm1.1Jimw/Fpr2tm1.1Jimw
Tg(Vil1-cre)997Gum/0 		involves: 129X1/SvJ * C57BL/6J * SJL MGI:5504261


Genotype
MGI:5503981
cn1
Allelic
Composition		 Fpr2tm1.1Jimw/Fpr2tm1.1Jimw
Lyz2tm1(cre)Ifo/Lyz2+
Genetic
Background		 involves: 129P2/OlaHsd * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fpr2tm1.1Jimw mutation (0 available); any Fpr2 mutation (24 available)
Lyz2tm1(cre)Ifo mutation (14 available); any Lyz2 mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
decreased susceptibility to induced colitis ( J:197568 )
• DSS treated mice exhibit moderately reduced disease with reduced inflammation compared with control mice

immune system
decreased susceptibility to induced colitis ( J:197568 )
• DSS treated mice exhibit moderately reduced disease with reduced inflammation compared with control mice




Genotype
MGI:5504261
cn2
Allelic
Composition		 Fpr2tm1.1Jimw/Fpr2tm1.1Jimw
Tg(Vil1-cre)997Gum/0
Genetic
Background		 involves: 129X1/SvJ * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fpr2tm1.1Jimw mutation (0 available); any Fpr2 mutation (24 available)
Tg(Vil1-cre)997Gum mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Decreased colon crypt length in Fpr2tm1.1Jimw/Fpr2tm1.1Jimw Tg(Vil1-cre)997Gum/0 mice

digestive/alimentary system
abnormal large intestine crypts of Lieberkuhn morphology ( J:197568 )
• shorter than normal colonic crypts

endocrine/exocrine glands
abnormal large intestine crypts of Lieberkuhn morphology ( J:197568 )
• shorter than normal colonic crypts




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory