Phenotypes associated with this allele

• Allele Symbol: Hmgxb3^{tm1a(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4460446
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hmgxb3^tm1a(EUCOMM)Wtsi/Hmgxb3^tm1a(EUCOMM)Wtsi	C57BL/6N-Hmgxb3^tm1a(EUCOMM)Wtsi/Wtsi	MGI:6102815

Genotype
MGI:6102815

hm1

• Allelic Composition: Hmgxb3^{tm1a(EUCOMM)Wtsi}/Hmgxb3^{tm1a(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Hmgxb3^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0593_2_E04

Data Sources

IMPC Data for Hmgxb3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal ductus venosus valve morphology ( J:239583 )

DMDD

absent ductus venosus valve ( J:239583 )

DMDD

abnormal inferior vena cava morphology ( J:239583 )

DMDD

craniofacial

basisphenoid bone foramen ( J:239583 )

DMDD

hearing/vestibular/ear

abnormal inner ear morphology ( J:239583 )

DMDD

homeostasis/metabolism

subcutaneous edema ( J:239583 )

DMDD

immune system

blood in lymph vessels ( J:239583 )

DMDD

integument

subcutaneous edema ( J:239583 )

DMDD

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - WTSI

muscle

abnormal eye muscle morphology ( J:239583 )

DMDD

neoplasm

increased hemangioma incidence ( J:239583 )

DMDD

nervous system

exencephaly ( J:239583 )

DMDD

abnormal hypoglossal nerve topology ( J:239583 )

DMDD

absent hypoglossal nerve ( J:239583 )

DMDD

thin hypoglossal nerve ( J:239583 )

DMDD

skeleton

basisphenoid bone foramen ( J:239583 )

DMDD

vision/eye

abnormal eye muscle morphology ( J:239583 )

DMDD

abnormal optic cup morphology ( J:239583 )

DMDD