About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tor1aip1Gt(GST004691)Lex
gene trap GST004691
MGI:4460952
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tor1aip1Gt(GST004691)Lex/Tor1aip1Gt(GST004691)Lex Not Specified MGI:4460957
cx2
 		Tor1atm1Wtd/Tor1a+
Tor1aip1Gt(GST004691)Lex/Tor1aip1+ 		involves: 129S1/Sv MGI:4460959


Genotype
MGI:4460957
hm1
Allelic
Composition		 Tor1aip1Gt(GST004691)Lex/Tor1aip1Gt(GST004691)Lex
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tor1aip1Gt(GST004691)Lex mutation (0 available); any Tor1aip1 mutation (42 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
perinatal lethality, complete penetrance ( J:160544 )
• mice die between E18 and P0

cellular
abnormal cell nucleus morphology ( J:160544 )
• nuclear membranes from neural tissue and cultured neurons are abnormal with perinuclear blebs compared to in wild-type cells
• nuclear membranes from nonneural tissues exhibit blebs unlike in wild-type cells




Genotype
MGI:4460959
cx2
Allelic
Composition		 Tor1atm1Wtd/Tor1a+
Tor1aip1Gt(GST004691)Lex/Tor1aip1+
Genetic
Background		 involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tor1aip1Gt(GST004691)Lex mutation (0 available); any Tor1aip1 mutation (42 available)
Tor1atm1Wtd mutation (1 available); any Tor1a mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell nucleus morphology ( J:160544 )
• nuclear blebs are observed unlike in single heterozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory