Phenotypes associated with this allele

• Allele Symbol: Prrc2b^{tm1a(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4461729
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prrc2b^tm1a(EUCOMM)Wtsi/Prrc2b^tm1a(EUCOMM)Wtsi	C57BL/6N-Prrc2b^tm1a(EUCOMM)Wtsi/Wtsi	MGI:5883884

Genotype
MGI:5883884

hm1

• Allelic Composition: Prrc2b^{tm1a(EUCOMM)Wtsi}/Prrc2b^{tm1a(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Prrc2b^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0599_5_H02

Data Sources

IMPC Data for Prrc2b

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

persistent right dorsal aorta ( J:239583 )

DMDD

persistent right 6th pharyngeal arch artery ( J:239583 )

DMDD

persistent trigeminal artery ( J:239583 )

DMDD

right aortic arch ( J:239583 )

DMDD

left sided brachiocephalic trunk ( J:239583 )

DMDD

absent segment of posterior cerebral artery ( J:239583 )

DMDD

dilated liver sinusoidal space ( J:239583 )

DMDD

abnormal vitelline vein topology ( J:239583 )

DMDD

arteriovenous malformation ( J:239583 )

DMDD

dilated vasculature ( J:239583 )

DMDD

perimembraneous ventricular septal defect ( J:239583 )

DMDD

abnormal pulmonary valve cusp morphology ( J:239583 )

DMDD

hemorrhage ( J:239583 )

DMDD

eye hemorrhage ( J:239583 )

DMDD

craniofacial

persistent right 6th pharyngeal arch artery ( J:239583 )

DMDD

absent hypoglossal canal ( J:239583 )

DMDD

embryo

persistent right 6th pharyngeal arch artery ( J:239583 )

DMDD

abnormal vitelline vein topology ( J:239583 )

DMDD

endocrine/exocrine glands

abnormal thyroid gland morphology ( J:239583 )

DMDD

homeostasis/metabolism

retropleural edema ( J:239583 )

DMDD

liver/biliary system

dilated liver sinusoidal space ( J:239583 )

DMDD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI

muscle

abnormal eye muscle morphology ( J:239583 )

DMDD

abnormal skeletal muscle morphology ( J:239583 )

DMDD

absent skeletal muscle ( J:239583 )

DMDD

nervous system

absent segment of posterior cerebral artery ( J:239583 )

DMDD

abnormal forebrain morphology ( J:239583 )

DMDD

abnormal hypoglossal nerve topology ( J:239583 )

DMDD

absent hypoglossal nerve ( J:239583 )

DMDD

skeleton

absent hypoglossal canal ( J:239583 )

DMDD

fusion of vertebral arches ( J:239583 )

DMDD

vision/eye

eye hemorrhage ( J:239583 )

DMDD

abnormal eye morphology ( J:239583 )

DMDD

abnormal eye muscle morphology ( J:239583 )

DMDD

lens vacuoles ( J:239583 )

DMDD

abnormal optic cup morphology ( J:239583 )

DMDD