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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ccna2tm1.2Pisc
targeted mutation 1.2, Piotr Sicinski
MGI:4461956
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ccna2tm1.2Pisc/Ccna2tm1.2Pisc involves: 129S4/SvJaeSor MGI:4461992
cn2
 		Ccna1tm1Djw/Ccna1tm1Djw
Ccna2tm1.1Pisc/Ccna2tm1.2Pisc 		involves: 129S4/SvJaeSor * 129S7/SvEvBrd MGI:4461990


Genotype
MGI:4461992
hm1
Allelic
Composition		 Ccna2tm1.2Pisc/Ccna2tm1.2Pisc
Genetic
Background		 involves: 129S4/SvJaeSor
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccna2tm1.2Pisc mutation (0 available); any Ccna2 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:4461990
cn2
Allelic
Composition		 Ccna1tm1Djw/Ccna1tm1Djw
Ccna2tm1.1Pisc/Ccna2tm1.2Pisc
Genetic
Background		 involves: 129S4/SvJaeSor * 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccna1tm1Djw mutation (0 available); any Ccna1 mutation (28 available)
Ccna2tm1.1Pisc mutation (0 available); any Ccna2 mutation (15 available)
Ccna2tm1.2Pisc mutation (0 available); any Ccna2 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
decreased cell proliferation ( J:155178 )
• cre-transduced embryonic stem cells fail to proliferate unlike similarly treated double heterozygous cells




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory