reproductive system
• Separation of the sperm head and tail was observed in spermatozoa in the cauda epididymis
• the capitulum and striated columns were not apparent in the cytoplasm of the separated head
• almost all of the sperm heads from the homozygous null mice were detached from tails when cultured
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• homozygous males and wild-type females did not result in any successful pregnancies, however vaginal plugs were observed in the paired wild-type females
• body mass, the weights of testes and seminal vesicles, the serum testosterone level and polyamine contents are normal
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• tailless sperm heads showed no response to the ionophore and acrosome reaction did not take place; however, heads were capable of fertilizing eggs via intracytoplasmic sperm injection
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cellular
• Separation of the sperm head and tail was observed in spermatozoa in the cauda epididymis
• the capitulum and striated columns were not apparent in the cytoplasm of the separated head
• almost all of the sperm heads from the homozygous null mice were detached from tails when cultured
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