Analysis Tools|
Allele Symbol Allele Name Allele ID |
Slc6a9tm1Veul targeted mutation 1, Volker Eulenburg MGI:4818447 |
||||||||||||||||||||
| Summary |
4 genotypes
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• no hypotonia
|
| N |
• no motor defects seen in open field or rotarod tests
|
|
• GlyT1 specific uptake of glycine by hippocampal membranes is reduced 50%
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• die within 8 hours of birth
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• hypotonic phenotype leads to premature death
• frequency of deaths peaks at around 3 days of age
• 20% of mice have a normal life span
|
|
• 80% of homozygotes show a strong hypotonic phenotype
• onset from day 1 through 10 days of age
• 20% of mice develop no phenotype
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 11/12/2024 MGI 6.24 |
|
|
|
||
