Phenotypes associated with this allele

• Allele Symbol: Crb2^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4818586
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Crb2^tm1a(KOMP)Wtsi/Crb2^tm1a(KOMP)Wtsi	C57BL/6N-Crb2^tm1a(KOMP)Wtsi/Wtsi	MGI:5631004
ht2	Crb2^tm1a(KOMP)Wtsi/Crb2^+	C57BL/6N-Crb2^tm1a(KOMP)Wtsi/Wtsi	MGI:5705975

Genotype
MGI:5631004

hm1

• Allelic Composition: Crb2^{tm1a(KOMP)Wtsi}/Crb2^{tm1a(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Crb2^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0603_1_B06

Data Sources

IMPC Data for Crb2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal chorion morphology ( J:261316 )

• unpatterned chorion

abnormal placenta morphology ( J:261316 )

• branching morphology defect

abnormal visceral yolk sac morphology ( J:261316 )

• yolk sac abnormalities

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI

embryonic lethality during organogenesis, complete penetrance ( J:261316 )

• lethality at E9.5-E10.5

Genotype
MGI:5705975

ht2

• Allelic Composition: Crb2^{tm1a(KOMP)Wtsi}/Crb2⁺
• Genetic Background: C57BL/6N-Crb2^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0603_1_B06

Data Sources

IMPC Data for Crb2

integument

abnormal vibrissa morphology ( J:211773 )

♀

IMPC - WTSI

vision/eye

abnormal retina morphology ( J:211773 )

IMPC - WTSI