Phenotypes associated with this allele

• Allele Symbol: Ffar4^tm1Sdmk
• Allele Name: targeted mutation 1, Sami Damak
• Allele ID: MGI:4818767
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ffar4^tm1Sdmk/Ffar4^tm1Sdmk	C57BL/6J-Ffar4^tm1Sdmk	MGI:4818769

Genotype
MGI:4818769

hm1

• Allelic Composition: Ffar4^tm1Sdmk/Ffar4^tm1Sdmk
• Genetic Background: C57BL/6J-Ffar4^tm1Sdmk

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

taste/olfaction

abnormal gustatory system physiology ( J:161517 )

• show a diminished preference for linoleic acid in a 2 bottle preference test

• glossopharyngeal nerve responses to oleic acid, linoleic acid or linolenic acid are diminished compared to responses in control mice

• chorda tympani nerve responses to oleic acid, linoleic acid or DHA are diminished compared to responses in control mice

abnormal taste sensitivity ( J:161517 )

• indifferent to all concentrations of linoleic acid and oleic acid suggesting a profound defect in the ability to taste these fatty acids

• no differences are detected in taste sensitivity for bitter, sweet, sour, salty or umami

nervous system

abnormal sensory neuron physiology ( J:161517 )

• glossopharyngeal nerve responses to oleic acid, linoleic acid or linolenic acid are diminished compared to responses in control mice

• chorda tympani nerve responses to oleic acid, linoleic acid or DHA are diminished compared to responses in control mice