All Phenotypes Itga5<tm2.1Hyn> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Itga5^tm2.1Hyn
targeted mutation 2.1, Richard Hynes
MGI:4818933

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Itga5^tm2.1Hyn/Itga5^tm2.1Hyn	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	MGI:4818934

Allelic Composition	Itga5^tm2.1Hyn/Itga5^tm2.1Hyn
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itga5^tm2.1Hyn mutation (0 available); any Itga5 mutation (47 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• die around E11

embryo

embryonic growth retardation ( J:161850 )

• embryos at E10.5 are severely growth retarded

incomplete somite formation ( J:161850 )

• posterior somites

growth/size/body

embryonic growth retardation ( J:161850 )

• embryos at E10.5 are severely growth retarded

cardiovascular system

abnormal blood vessel morphology ( J:161850 )

• reduced vascularization

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24