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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Thy1-BACE1)54/4Ppa
transgene insertion 54/4, Paolo Paganetti
MGI:4819402
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Tg(Thy1-APPDutch)#Jckr/0
Tg(Thy1-BACE1)54/4Ppa/0
involves: C57BL/6 MGI:4819593


Genotype
MGI:4819593
cx1
Allelic
Composition
Tg(Thy1-APPDutch)#Jckr/0
Tg(Thy1-BACE1)54/4Ppa/0
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Thy1-APPDutch)#Jckr mutation (1 available)
Tg(Thy1-BACE1)54/4Ppa mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system

homeostasis/metabolism
• extensive vascular amyloid in the thalamus
• parenchymal amyloid in the cortex and some amyloid in the subiculum

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
cerebral amyloid angiopathy DOID:9246 J:162531





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory