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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ctcfltm1Vloc
targeted mutation 1, Victor Lobanenkov
MGI:4819543
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ctcfltm1Vloc/Ctcfltm1Vloc involves: 129S1/Sv * C57BL/6 MGI:4819553


Genotype
MGI:4819553
hm1
Allelic
Composition		 Ctcfltm1Vloc/Ctcfltm1Vloc
Genetic
Background		 involves: 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctcfltm1Vloc mutation (0 available); any Ctcfl mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:162590 )
N
• male mice are fertile
abnormal testis morphology ( J:162590 )
• testes contain multinucleated cells unlike in wild-type mice indicating a spermatogenesis defect
abnormal spermatogenesis ( J:162590 )
• testes contain multinucleated cells unlike in wild-type mice indicating a spermatogenesis defect
abnormal male meiosis ( J:162590 )
• as early as P21, testes produce fewer haploid cells (spermatids) than in wild-type mice

endocrine/exocrine glands
abnormal testis morphology ( J:162590 )
• testes contain multinucleated cells unlike in wild-type mice indicating a spermatogenesis defect

cellular
abnormal male meiosis ( J:162590 )
• as early as P21, testes produce fewer haploid cells (spermatids) than in wild-type mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory