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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Vmn2r116tm1.1Ktou
targeted mutation 1.1, Kazushige Touhara
MGI:4819730
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Vmn2r116tm1.1Ktou/Vmn2r116tm1.1Ktou C57BL/6-Vmn2r116tm1.1Ktou MGI:4819737
hm2
 		Vmn2r116tm1.1Ktou/Vmn2r116tm1.1Ktou involves: C57BL/6 MGI:6506259


Genotype
MGI:4819737
hm1
Allelic
Composition		 Vmn2r116tm1.1Ktou/Vmn2r116tm1.1Ktou
Genetic
Background		 C57BL/6-Vmn2r116tm1.1Ktou
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vmn2r116tm1.1Ktou mutation (0 available); any Vmn2r116 mutation (49 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal sexual interaction ( J:162636 )
• ESP1(Gm6084)-stimulated female mice fail to exhibit an increase in lordosis behavior and successful intromission by males unlike similarly treated wild-type mice




Genotype
MGI:6506259
hm2
Allelic
Composition		 Vmn2r116tm1.1Ktou/Vmn2r116tm1.1Ktou
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vmn2r116tm1.1Ktou mutation (0 available); any Vmn2r116 mutation (49 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
abnormal vomeronasal organ morphology ( J:267556 )
• trend for an increase in the number of cells positive for phosphorylated ribosomal protein pS6

growth/size/body
abnormal vomeronasal organ morphology ( J:267556 )
• trend for an increase in the number of cells positive for phosphorylated ribosomal protein pS6

nervous system
abnormal vomeronasal organ morphology ( J:267556 )
• trend for an increase in the number of cells positive for phosphorylated ribosomal protein pS6
abnormal vomeronasal organ physiology ( J:267556 )
• exposure to ESP1 fails to induce expression of phosphorylated ribosomal protein pS6

respiratory system
abnormal vomeronasal organ morphology ( J:267556 )
• trend for an increase in the number of cells positive for phosphorylated ribosomal protein pS6




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/03/2024
MGI 6.24 		The Jackson Laboratory