About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Vmn2r116tm1.1Ktou
targeted mutation 1.1, Kazushige Touhara
MGI:4819730
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Vmn2r116tm1.1Ktou/Vmn2r116tm1.1Ktou C57BL/6-Vmn2r116tm1.1Ktou MGI:4819737
hm2
 		Vmn2r116tm1.1Ktou/Vmn2r116tm1.1Ktou involves: C57BL/6 MGI:6506259


Genotype
MGI:4819737
hm1
Allelic
Composition		 Vmn2r116tm1.1Ktou/Vmn2r116tm1.1Ktou
Genetic
Background		 C57BL/6-Vmn2r116tm1.1Ktou
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vmn2r116tm1.1Ktou mutation (0 available); any Vmn2r116 mutation (49 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal sexual interaction ( J:162636 )
• ESP1(Gm6084)-stimulated female mice fail to exhibit an increase in lordosis behavior and successful intromission by males unlike similarly treated wild-type mice




Genotype
MGI:6506259
hm2
Allelic
Composition		 Vmn2r116tm1.1Ktou/Vmn2r116tm1.1Ktou
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vmn2r116tm1.1Ktou mutation (0 available); any Vmn2r116 mutation (49 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
abnormal vomeronasal organ morphology ( J:267556 )
• trend for an increase in the number of cells positive for phosphorylated ribosomal protein pS6

growth/size/body
abnormal vomeronasal organ morphology ( J:267556 )
• trend for an increase in the number of cells positive for phosphorylated ribosomal protein pS6

nervous system
abnormal vomeronasal organ morphology ( J:267556 )
• trend for an increase in the number of cells positive for phosphorylated ribosomal protein pS6
abnormal vomeronasal organ physiology ( J:267556 )
• exposure to ESP1 fails to induce expression of phosphorylated ribosomal protein pS6

respiratory system
abnormal vomeronasal organ morphology ( J:267556 )
• trend for an increase in the number of cells positive for phosphorylated ribosomal protein pS6




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory