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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
ComtB2i
B2 insertion
MGI:4819952
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
ComtB2i/ComtB2i Boulder heterogeneous stock MGI:4819969
ht2
ComtB2i/Comt+ Boulder heterogeneous stock MGI:4819971


Genotype
MGI:4819969
hm1
Allelic
Composition
ComtB2i/ComtB2i
Genetic
Background
Boulder heterogeneous stock
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
ComtB2i mutation (0 available); any Comt mutation (24 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• on seven behavioral tests other than novel object exploration, male mice homozygous for this mutation show no significant differences from heterozygous mutant or wild-type male mice
• homozygous mutant male mice visit a novel object less frequently than do homozygous wild-type but more frequently than heterozygous males
• homozygous mutant male mice spend less time exploring a novel object than do homozygous wild-type but more frequently than heterozygous males




Genotype
MGI:4819971
ht2
Allelic
Composition
ComtB2i/Comt+
Genetic
Background
Boulder heterogeneous stock
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
ComtB2i mutation (0 available); any Comt mutation (24 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• on seven behavioral tests other than novel object exploration, male mice heterozygous for this mutation show no significant differences from homozygous mutant or wild-type male mice
• male mice heterozygous for this mutation visit a novel object less frequently than do either homozygous mutant or wild-type males
• heterozygous mutant male mice spend less time exploring a novel object than do either homozygous mutant or wild-type males





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory