Analysis Tools|
Allele Symbol Allele Name Allele ID |
Kidins220tm1.1Mvc targeted mutation 1.1, Moses V Chao MGI:4820793 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• between 1 and 3 months, mice fail to exhibit an increase in dendritic complexity in the barrel somatosensory cortex unlike in wild-type mice
• at 3 months, mice exhibit decreased dendritic complexity in the dentate gyrus compared with wild-type mice
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• in vivo, dendritic spines of pyramidal neurons are less stable than spines on wild-type cells
• however, spine formation rate is normal
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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