Phenotypes associated with this allele

• Allele Symbol: Tpi1^a-m6Neu
• Allele Name: mutation 6, Neuherberg
• Allele ID: MGI:4821798
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tpi1^a-m6Neu/Tpi1^a-m6Neu	involves: 101/El * C3H/El	MGI:4821799
ht2	Tpi1^a-m6Neu/Tpi1^+	involves: 101/El * C3H/El	MGI:4821800

Genotype
MGI:4821799

hm1

• Allelic Composition: Tpi1^a-m6Neu/Tpi1^a-m6Neu
• Genetic Background: involves: 101/El * C3H/El

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

increased spleen weight ( J:163223 )

• spleen somatic index is increased compared to in wild-type mice

hemolytic anemia ( J:163223 )

decreased hematocrit ( J:163223 )

decreased hemoglobin content ( J:163223 )

decreased mean corpuscular hemoglobin concentration ( J:163223 )

increased mean corpuscular volume ( J:163223 )

homeostasis/metabolism

abnormal enzyme/coenzyme activity ( J:163223 )

• triosephosphate isomerase activity in the blood, lung, spleen, heart, liver, kidney, and brain is reduced compared to in wild-type mice

immune system

increased spleen weight ( J:163223 )

• spleen somatic index is increased compared to in wild-type mice

growth/size/body

increased spleen weight ( J:163223 )

• spleen somatic index is increased compared to in wild-type mice

Genotype
MGI:4821800

ht2

• Allelic Composition: Tpi1^a-m6Neu/Tpi1⁺
• Genetic Background: involves: 101/El * C3H/El

homeostasis/metabolism

abnormal enzyme/coenzyme activity ( J:163223 )

• triosephosphate isomerase activity in the blood, lung, spleen, heart, liver, kidney, and brain is reduced compared to in wild-type mice