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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Stat1tm1Mam
targeted mutation 1, Lothar Hennighausen
MGI:4821871
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Stat1tm1Mam/Stat1tm1Mam
Tg(Wap-cre)11738Mam/0 		involves: 129S/SvEv * C57BL/6 * SJL MGI:4942395
cn2
 		Stat1tm1Mam/Stat1tm1Mam
Tg(MMTV-Erbb2*,-cre)1Mul/0 		involves: 129S/SvEv * FVB MGI:4821942
cn3
 		Stat1tm1Mam/Stat1tm1Mam
Tg(MMTV-cre)#Mam/0 		involves: 129S/SvEv * FVB MGI:4942394


Genotype
MGI:4942395
cn1
Allelic
Composition		 Stat1tm1Mam/Stat1tm1Mam
Tg(Wap-cre)11738Mam/0
Genetic
Background		 involves: 129S/SvEv * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stat1tm1Mam mutation (1 available); any Stat1 mutation (74 available)
Tg(Wap-cre)11738Mam mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
integument phenotype ( J:169262 )
N
• female mice exhibit normal mammary gland architecture




Genotype
MGI:4821942
cn2
Allelic
Composition		 Stat1tm1Mam/Stat1tm1Mam
Tg(MMTV-Erbb2*,-cre)1Mul/0
Genetic
Background		 involves: 129S/SvEv * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stat1tm1Mam mutation (1 available); any Stat1 mutation (74 available)
Tg(MMTV-Erbb2*,-cre)1Mul mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
decreased tumor latency ( J:169262 )
• median time to tumor onset is 49 weeks compared with 62 weeks for Tg(MMTV-Erbb2*,-cre)1Mul mice




Genotype
MGI:4942394
cn3
Allelic
Composition		 Stat1tm1Mam/Stat1tm1Mam
Tg(MMTV-cre)#Mam/0
Genetic
Background		 involves: 129S/SvEv * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stat1tm1Mam mutation (1 available); any Stat1 mutation (74 available)
Tg(MMTV-cre)#Mam mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
integument phenotype ( J:169262 )
N
• female mice exhibit normal lactation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory