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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Col4a1Acso
anterior capsular and suture opacity
MGI:4822140
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Col4a1Acso/Col4a1Acso C3.Cg-Col4a1Acso MGI:4822365
ht2
 		Col4a1Acso/Col4a1+ C3.Cg-Col4a1Acso MGI:4822226


Genotype
MGI:4822365
hm1
Allelic
Composition		 Col4a1Acso/Col4a1Acso
Genetic
Background		 C3.Cg-Col4a1Acso
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col4a1Acso mutation (1 available); any Col4a1 mutation (78 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
lethality throughout fetal growth and development, complete penetrance ( J:163225 )
• reduced numbers of embryos consistent with death of all homozygotes
• no homozygotes at birth




Genotype
MGI:4822226
ht2
Allelic
Composition		 Col4a1Acso/Col4a1+
Genetic
Background		 C3.Cg-Col4a1Acso
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col4a1Acso mutation (1 available); any Col4a1 mutation (78 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal lens capsule morphology ( J:163225 )
• anterior capsule opacity
sutural cataract ( J:163225 )
• sutural opacity

nervous system
nervous system phenotype ( J:163225 )
N
• no histological abnormalities observed in the brain

hematopoietic system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory