Phenotypes associated with this allele

• Allele Symbol: Col4a2^ENU415
• Allele Name: ENU mutation 415
• Allele ID: MGI:4822169
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Col4a2^ENU415/Col4a2^ENU415	C3.Cg-Col4a2^ENU415	MGI:4822373
ht2	Col4a2^ENU415/Col4a2^+	C3.Cg-Col4a2^ENU415	MGI:4822253

Genotype
MGI:4822373

hm1

• Allelic Composition: Col4a2^ENU415/Col4a2^ENU415
• Genetic Background: C3.Cg-Col4a2^ENU415

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:163225 )

• all die by weaning

prenatal lethality, incomplete penetrance ( J:163225 )

• reduced numbers of homozygotes born

cardiovascular system

hemorrhage ( J:163225 )

• extensive whole body hemorrhage at E15

Genotype
MGI:4822253

ht2

• Allelic Composition: Col4a2^ENU415/Col4a2⁺
• Genetic Background: C3.Cg-Col4a2^ENU415

vision/eye

increased cornea thickness ( J:163225 )

• cornea is thickened

abnormal eye anterior chamber morphology ( J:163225 )

• reduced distance separating the cornea and the lens

cataract ( J:163225 )

• examples of total lens opacity

microphthalmia ( J:163225 )

hematopoietic system

decreased erythrocyte cell number ( J:163225 )

decreased hematocrit ( J:163225 )

decreased hemoglobin content ( J:163225 )

nervous system

abnormal brain morphology ( J:163225 )

• abnormalities observed in some but not all mice

cardiovascular system

hemorrhage ( J:163225 )